KCNN2

Across TCGA cell cohorts, KCNN2 mutation is significantly associated with the RNA expression of many other genes, with 324 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNN2-associated genes across cancer lineages are RSC1A1, DMRTB1, and GLOD5. Each is linked with KCNN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNN2-to-partner and partner-to-KCNN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RSC1A1 grouped by KCNN2-low versus KCNN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN2→partner) and Y-score (partner→KCNN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RSC1A1 →	+1.112	+3.799	<.001	<.001	3	2
BLOOD_Lymphoma	DMRTB1 →	+0.019	+3.544	<.001	.001	3	1
BLOOD_Lymphoma	GLOD5 →	+0.050	+3.643	<.001	.001	3	1
BLOOD_Lymphoma	ZNF804B →	+0.012	+3.180	<.001	.004	3	1
BLOOD_Lymphoma	MEIKIN →	+0.140	+3.169	.001	.008	3	1
PANCREAS	OCSTAMP →	+0.046	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 324 associations by consensus.

RSC1A1 by KCNN2 expression — LARGE_INTESTINE

Explore this box plot interactively →