KCNMB3

Across TCGA patient cohorts, KCNMB3 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNMB3-associated genes across cancer lineages are HNRNPA1P58, OR10A5, and DIS3L2P1. Each is linked with KCNMB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB3-to-partner and partner-to-KCNMB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPA1P58 grouped by KCNMB3-low versus KCNMB3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB3→partner) and Y-score (partner→KCNMB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HNRNPA1P58 →	+0.203	+3.877	<.001	.004	3	2
HNSC	OR10A5 →	+0.055	+5.241	<.001	.007	3	2
HNSC	DIS3L2P1 →	+0.159	+5.124	.005	.008	3	2
LIHC	RN7SKP47 →	+0.099	+6.479	<.001	.001	3	2
LIHC	USP12PY →	+0.031	+5.647	<.001	.004	3	2
HNSC	TUBB1P1 →	+0.048	+6.111	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

HNRNPA1P58 by KCNMB3 expression — COAD

Explore this box plot interactively →