Across TCGA cell cohorts, KCNMB2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNMB2-associated genes across cancer lineages are TRDN, BHLHE23, and USP17L20. Each is linked with KCNMB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB2-to-partner and partner-to-KCNMB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB2→partner) and Y-score (partner→KCNMB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRDN →	+0.040	+4.054	<.001	.004	3	1
UPPER_AERODIGESTIVE_TRACT	BHLHE23 →	+0.032	+4.357	<.001	.006	3	1
BLOOD_Leukemia	USP17L20 →	+0.006	+5.539	<.001	.003	3	1
BLOOD_Leukemia	USP17L18 →	+0.006	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

KCNMB2 survival (RNA) · tumor vs normal (RNA) · all KCNMB2 data types