KCNMB2-AS1

Across TCGA pan-cancer cohorts, KCNMB2-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of KCNMB2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KCNMB2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KCNMB2-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, COAD, and THCA are the cancer types where KCNMB2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNMB2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+2.477	<.001	12	view →
COAD	All	All	+0.931	<.001	10	view →
THCA	All	III,IV	+0.427	<.001	9	view →
LUSC	Female	All	+4.027	<.001	8	view →
BLCA	All	All	+1.744	<.001	8	view →
LUAD	Male	All	+1.573	<.001	8	view →
LIHC	All	II,III,IV	+1.040	<.001	8	view →
UCEC	All	III,IV	+2.447	<.001	6	view →
STAD	All	II,III,IV	+1.129	<.001	6	view →
KIRC	All	All	+0.169	.007	6	view →
READ	All	All	+1.463	<.001	5	view →
BRCA	All	II,III,IV	+0.473	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

KCNMB2-AS1–HNSC

Open the HNSC breakdown →