KCNMB1

Across TCGA pan-cancer cohorts, KCNMB1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KCNMB1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher KCNMB1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KCNMB1 expression acts as an unfavorable survival marker.

MESO, COAD, and SARC are the cancer types where KCNMB1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
COAD	DFS	Median	All	0.140	0.781	<.001	9	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KCNMB1–MESO (DFS)

Open the MESO breakdown →