KCNMB1

Across TCGA patient cohorts, KCNMB1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KCNMB1-associated genes across cancer lineages are Rictor_pT1135, Cyclin-D1, and Myosin-IIa_pS1943. Each is linked with KCNMB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNMB1-to-partner and partner-to-KCNMB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by KCNMB1-low versus KCNMB1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB1→partner) and Y-score (partner→KCNMB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Rictor_pT1135 →	+0.267	+3.017	.002	.019	1	3
SKCM	Cyclin-D1 →	+0.601	+2.820	<.001	.035	3	1
SKCM	Myosin-IIa_pS1943 →	-0.623	-2.982	<.001	.036	2	1
SKCM	CDK1 →	+0.270	+3.000	.006	.036	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Rictor_pT1135 by KCNMB1 expression — SKCM

Explore this box plot interactively →