KCNMA1-AS1

Across TCGA pan-cancer cohorts, KCNMA1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KCNMA1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher KCNMA1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNMA1-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and STAD show a favorable association.

MESO, ACC, and CHOL are the cancer types where KCNMA1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.215	0.505	<.001	76	view →
ACC	DFS	Quartile	All	0.424	0.802	.002	40	view →
CHOL	DFS	Tertile	All	0.140	0.662	.001	35	view →
ESCA	DFS	Median	III,IV	0.572	0.309	.002	31	view →
STAD	OS	Median	IV	0.527	0.226	.013	30	view →
KIRP	DFS	Median	IV	0.035	0.458	.018	24	view →
DLBC	OS	Quartile	All	0.606	1.000	.016	23	view →
OV	OS	Median	All	0.353	0.285	.026	20	view →
THCA	OS	Tertile	III,IV	0.730	1.000	.007	16	view →
LUSC	DFS	Tertile	III,IV	0.383	1.000	.008	15	view →
SKCM	OS	Tertile	III,IV	0.845	0.694	.008	13	view →
READ	DFS	Tertile	IV	0.204	0.936	.038	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KCNMA1-AS1–MESO (OS)

Open the MESO breakdown →