KCNK7

Across TCGA patient cohorts, KCNK7 mutation is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KCNK7-associated genes across cancer lineages are RNA5SP394, RNU6-1305P, and MIR301A. Each is linked with KCNK7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK7-to-partner and partner-to-KCNK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP394 grouped by KCNK7-low versus KCNK7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK7→partner) and Y-score (partner→KCNK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP394 →	+0.393	+3.620	<.001	.004	3	2
COAD	RNU6-1305P →	+0.496	+4.385	<.001	<.001	3	2
COAD	MIR301A →	+0.922	+3.476	<.001	.005	3	2
COAD	RNU5E-9P →	+0.166	+4.824	<.001	.002	3	2
COAD	AGBL4-IT1 →	+0.455	+3.366	<.001	.002	3	2
COAD	RN7SL223P →	+0.154	+4.824	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

RNA5SP394 by KCNK7 expression — COAD

Explore this box plot interactively →