KCNK7

Across TCGA cell cohorts, KCNK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,641 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNK7-associated GO terms across cancer lineages are DNA damage checkpoint signaling, DNA integrity checkpoint signaling, and Mitotic cell cycle checkpoint signaling. Each is linked with KCNK7 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCNK7-to-partner and partner-to-KCNK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA damage checkpoint signaling grouped by KCNK7-low versus KCNK7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK7→partner) and Y-score (partner→KCNK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA damage checkpoint signaling →	+0.090	+0.447	.001	.003	3	8
BONE	DNA integrity checkpoint signaling →	+0.101	+0.512	.008	.007	3	6
BONE	Mitotic cell cycle checkpoint signaling →	+0.133	+0.485	.003	<.001	3	6
BONE	Regulation of chromosome organization →	+0.102	+0.492	.002	.004	3	6
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.125	+0.594	<.001	.003	3	6
BONE	Negative regulation of RNA splicing →	+0.129	+0.571	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,641 associations by consensus.

DNA damage checkpoint signaling by KCNK7 expression — BONE

Explore this box plot interactively →