KCNK6

Across TCGA patient cohorts, KCNK6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,928 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNK6-associated genes across cancer lineages are GNG8, KBTBD11, and C8G. Each is linked with KCNK6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK6-to-partner and partner-to-KCNK6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNK6 versus GNG8 in BRCA, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK6→partner) and Y-score (partner→KCNK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GNG8 →	+0.950	+0.986	.001	.002	3	1
BRCA	KBTBD11 →	-1.274	-1.098	.009	.002	3	1
BRCA	C8G →	+1.466	+0.986	.001	.002	3	1
BRCA	TRAJ33 →	+2.179	+0.797	<.001	.005	3	1
BRCA	VDAC1P7 →	+0.273	+0.797	<.001	.005	3	1
BRCA	RN7SKP273 →	+0.436	+0.797	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,928 associations by consensus.

KCNK6 vs GNG8 — BRCA

Explore this scatter interactively →