Across TCGA patient cohorts, KCNK4 protein abundance is significantly associated with the RNA expression of many other genes, with 305 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNK4-associated genes across cancer lineages are KCTD17, ASB2, and SRP54. Each is linked with KCNK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK4-to-partner and partner-to-KCNK4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK4→partner) and Y-score (partner→KCNK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KCTD17 →	-0.573	-1.408	<.001	.002	3	1
GBM	ASB2 →	-0.341	-1.056	.008	.004	3	1
GBM	SRP54 →	+0.348	+1.075	.003	.003	3	1
GBM	PTK6 →	+0.574	+1.371	.006	.002	3	1
GBM	SEL1L2 →	-0.124	-1.439	.001	.001	3	1
GBM	MAGED2 →	-0.358	-1.387	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 305 associations by consensus.

Exploration

KCNK4 survival (RNA) · tumor vs normal (RNA) · all KCNK4 data types