Across TCGA patient cohorts, KCNK4 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNK4-associated genes across cancer lineages are Ku80, MEK1, and MYH11. Each is linked with KCNK4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK4-to-partner and partner-to-KCNK4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK4→partner) and Y-score (partner→KCNK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.287	+3.009	.020	.019	3	1
UCEC	MEK1 →	+0.528	+3.321	.005	.010	3	1
UCEC	MYH11 →	+1.573	+3.000	.008	.036	3	1
UCEC	PKC-a →	+0.511	+2.820	.016	.035	3	1
UCEC	VEGFR2 →	+0.430	+3.009	.005	.019	3	1
UCEC	Caveolin-1 →	+0.815	+3.321	.032	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

KCNK4 survival (RNA) · tumor vs normal (RNA) · all KCNK4 data types