KCNK17

Across TCGA patient cohorts, KCNK17 protein abundance is significantly associated with the RNA expression of many other genes, with 3,481 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KCNK17-associated genes across cancer lineages are TMEM26, TMEM26-AS1, and CCDC78. Each is linked with KCNK17 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNK17-to-partner and partner-to-KCNK17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNK17 versus TMEM26 in BRCA, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK17→partner) and Y-score (partner→KCNK17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM26 →	+1.952	+1.441	<.001	<.001	3	4
UCEC	TMEM26-AS1 →	+1.535	+0.737	<.001	<.001	3	3
LUAD	CCDC78 →	+1.428	+0.557	.002	.006	3	2
LUAD	IFFO2 →	-1.247	-0.662	.009	.008	3	2
LUAD	ERICH5 →	-2.877	-0.572	.004	.004	3	2
BRCA	ZNF37BP →	+0.685	+1.291	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,481 associations by consensus.

KCNK17 vs TMEM26 — BRCA

Explore this scatter interactively →