KCNK15

Across TCGA cell cohorts, KCNK15 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNK15-associated genes across cancer lineages are TBC1D21, GP9, and C20orf85. Each is linked with KCNK15 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK15-to-partner and partner-to-KCNK15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by KCNK15-low versus KCNK15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK15→partner) and Y-score (partner→KCNK15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GP9 →	+0.071	+4.196	.009	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.032	+5.969	<.001	.001	3	1
BLOOD_Leukemia	USP29 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	C1QL2 →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	TAAR6 →	+0.018	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TBC1D21 by KCNK15 expression — LARGE_INTESTINE

Explore this box plot interactively →