KCNK15-AS1

Across TCGA pan-cancer cohorts, KCNK15-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated KCNK15-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KCNK15-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNK15-AS1 expression acts as an unfavorable survival marker, although some lineages such as SARC and PAAD show a favorable association.

KIRP, KIRC, and BRCA are the cancer types where KCNK15-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.813	0.942	.003	74	view →
KIRC	DFS	Median	All	0.540	0.706	<.001	68	view →
BRCA	OS	Quartile	II,III,IV	0.492	0.707	.006	37	view →
UCEC	DFS	Median	All	0.570	0.714	<.001	36	view →
KICH	DFS	Tertile	All	0.728	1.000	.012	35	view →
READ	DFS	Tertile	II,III,IV	0.220	0.833	<.001	32	view →
SARC	OS	Tertile	All	0.616	0.322	<.001	22	view →
PAAD	DFS	Tertile	All	0.500	0.281	.014	20	view →
MESO	OS	Median	IV	0.803	0.364	.009	18	view →
BLCA	OS	Median	All	0.477	0.677	.011	18	view →
HNSC	OS	Quartile	All	0.328	0.487	.007	18	view →
UCS	OS	Median	IV	0.248	0.673	.033	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

KCNK15-AS1–KIRP (OS)

Open the KIRP breakdown →