KCNK15-AS1

Across TCGA pan-cancer cohorts, KCNK15-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of KCNK15-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KCNK15-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KCNK15-AS1 is over-expressed in tumor, although a few such as UCEC and KICH show the opposite, repressed pattern.

KIRP, BRCA, and KIRC are the cancer types where KCNK15-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNK15-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.810	<.001	9	view →
BRCA	All	III,IV	+0.726	<.001	6	view →
KIRC	Male	All	+0.246	<.001	6	view →
UCEC	All	III,IV	−0.842	.006	4	view →
KICH	Female	II,III,IV	−0.382	.004	2	view →
COAD	All	II,III,IV	+0.369	.014	2	view →
CHOL	All	All	+0.241	.026	2	view →
PRAD	All	All	−0.151	.026	2	view →
LUSC	All	III,IV	−0.350	.028	1	view →
LUSC	All	All	+0.180	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 9 lineages.

KCNK15-AS1–KIRP

Open the KIRP breakdown →