Across TCGA patient cohorts, KCNK12 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,538 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNK12-associated proteins across cancer lineages are ZMYM3, WDR5, and WRNIP1. Each is linked with KCNK12 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNK12-to-partner and partner-to-KCNK12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK12→partner) and Y-score (partner→KCNK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZMYM3 →	+0.358	+0.559	<.001	<.001	3	4
LSCC	WDR5 →	+0.225	+0.636	<.001	<.001	3	4
LSCC	WRNIP1 →	+0.405	+0.750	<.001	<.001	3	4
LSCC	ZCCHC3 →	+0.548	+0.688	<.001	.002	3	4
HNSC	ZFR →	+0.206	+0.554	<.001	<.001	3	4
LSCC	RPS6KA1 →	-0.257	-0.702	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,538 associations by consensus.

Exploration

KCNK12 survival (RNA) · tumor vs normal (RNA) · all KCNK12 data types