Across TCGA cell cohorts, KCNK12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,364 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KCNK12-associated GO terms across cancer lineages are Protein sumoylation, RNA splicing, via transesterification reactions, and Regulation of protein localization to centrosome. Each is linked with KCNK12 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCNK12-to-partner and partner-to-KCNK12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK12→partner) and Y-score (partner→KCNK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein sumoylation →	+0.081	+0.082	<.001	.003	2	11
BONE	RNA splicing, via transesterification reactions →	+0.074	+0.262	.002	.005	3	10
URINARY_TRACT	Regulation of protein localization to centrosome →	+0.118	+0.093	.001	.009	2	11
PANCREAS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.064	+0.077	<.001	<.001	3	9
PANCREAS	mRNA splicing, via spliceosome →	+0.064	+0.077	<.001	<.001	3	9
PANCREAS	RNA localization →	+0.086	+0.066	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,364 associations by consensus.

Exploration

KCNK12 survival (RNA) · tumor vs normal (RNA) · all KCNK12 data types