KCNK12

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNK12 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KCNK12-associated genes across cancer lineages are OCSTAMP and LILRA5. Each is linked with KCNK12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK12-to-partner and partner-to-KCNK12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK12→partner) and Y-score (partner→KCNK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADOCSTAMP →+0.020+4.343<.001.00231
LUNG_NSCLC_LUADLILRA5 →+0.036+4.189<.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration