KCNJ6-AS1

Across TCGA pan-cancer cohorts, KCNJ6-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated KCNJ6-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher KCNJ6-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNJ6-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

MESO, READ, and LGG are the cancer types where KCNJ6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
READ	DFS	Tertile	All	0.184	0.808	<.001	57	view →
LGG	OS	Tertile	All	0.326	0.494	<.001	43	view →
COAD	OS	Tertile	II,III,IV	0.427	0.801	<.001	42	view →
CESC	OS	Tertile	III,IV	0.345	0.725	.004	36	view →
THCA	OS	Tertile	IV	0.626	1.000	.002	27	view →
ESCA	DFS	Tertile	All	0.517	0.287	.022	24	view →
PAAD	DFS	Tertile	All	0.421	0.205	.012	19	view →
LIHC	OS	Tertile	All	0.612	0.793	.001	18	view →
LUAD	OS	Tertile	III,IV	0.324	0.680	.009	18	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	17	view →
SARC	DFS	Tertile	All	0.710	0.485	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

KCNJ6-AS1–MESO (OS)

Open the MESO breakdown →