KCNJ4

Across TCGA patient cohorts, KCNJ4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,142 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNJ4-associated proteins across cancer lineages are ITGA4, EHD4, and DIAPH2. Each is linked with KCNJ4 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNJ4-to-partner and partner-to-KCNJ4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ4 versus ITGA4 in GBM, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ4→partner) and Y-score (partner→KCNJ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGA4 →	-0.447	-0.850	<.001	<.001	3	4
GBM	EHD4 →	-0.428	-1.267	<.001	<.001	3	4
GBM	DIAPH2 →	-0.434	-1.408	<.001	<.001	3	3
LSCC	FAP →	-0.497	-0.101	<.001	.004	3	3
GBM	NF1_T2565 →	+0.412	+0.692	.002	.005	3	3
GBM	NFKB1 →	-0.347	-1.457	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,142 associations by consensus.

KCNJ4 vs ITGA4 — GBM

Explore this scatter interactively →