KCNJ4

Across TCGA patient cohorts, KCNJ4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,990 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNJ4-associated genes across cancer lineages are SNRPD3, GRK3, and SOX10. Each is linked with KCNJ4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ4-to-partner and partner-to-KCNJ4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ4 versus SNRPD3 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ4→partner) and Y-score (partner→KCNJ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.386	+0.443	.007	.003	3	1
GBM	GRK3 →	+0.611	+0.509	.001	<.001	3	1
GBM	SOX10 →	+1.156	+0.322	.003	.005	3	1
GBM	PICK1 →	+0.345	+0.491	.001	<.001	3	1
GBM	SLC16A8 →	+0.661	+0.399	<.001	.001	3	1
GBM	TPTEP1 →	+1.021	+0.366	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,990 associations by consensus.

KCNJ4 vs SNRPD3 — GBM

Explore this scatter interactively →