KCNJ4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCNJ4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,901 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCNJ4-associated GO terms across cancer lineages are Protein-DNA complex organization, DNA-templated transcription initiation, and Transcription initiation at RNA polymerase II promoter. Each is linked with KCNJ4 in more than 11 cancer types. Because this analysis shows association rather than direction, both KCNJ4-to-partner and partner-to-KCNJ4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by KCNJ4-low versus KCNJ4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ4→partner) and Y-score (partner→KCNJ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEProtein-DNA complex organization →+0.077+1.797<.001<.001312
OESOPHAGUSDNA-templated transcription initiation →+0.090+0.768<.001.008311
BONETranscription initiation at RNA polymerase II promoter →+0.090+1.935<.001<.001212
BONERenal vesicle formation →+1.302+1.781<.001<.001311
BONEMetanephric renal vesicle formation →+1.302+1.781<.001<.001311
BLOOD_LeukemiaCell fate commitment →-0.047-0.567<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,901 associations by consensus.

Protein-DNA complex organization by KCNJ4 expression — BONE

Box plot of Protein-DNA complex organization in KCNJ4-low vs KCNJ4-high samples in BONE.

Explore this box plot interactively →

Exploration