KCNJ16

Across TCGA cell cohorts, KCNJ16 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,495 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNJ16-associated GO terms across cancer lineages are Microtubule anchoring, Regulation of kidney size, and Regulation of serine-type endopeptidase activity. Each is linked with KCNJ16 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNJ16-to-partner and partner-to-KCNJ16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule anchoring grouped by KCNJ16-low versus KCNJ16-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ16→partner) and Y-score (partner→KCNJ16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule anchoring →	+0.085	+0.047	<.001	.001	3	6
SKIN	Regulation of kidney size →	+1.198	+0.035	<.001	.006	3	5
BLOOD_Leukemia	Regulation of serine-type endopeptidase activity →	-0.705	-0.445	<.001	.001	3	5
BLOOD_Leukemia	Positive regulation of serine-type endopeptidase activity →	-0.705	-0.445	<.001	.001	3	5
BONE	Cytoskeleton-dependent cytokinesis →	+0.073	+0.036	<.001	.003	3	4
LUNG_SCLC	Glycerophospholipid metabolic process →	+0.026	+0.303	.006	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,495 associations by consensus.

Microtubule anchoring by KCNJ16 expression — BONE

Explore this box plot interactively →