KCNJ14

Across TCGA patient cohorts, KCNJ14 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,049 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNJ14-associated proteins across cancer lineages are MSH2, SF3B3, and FOXK1. Each is linked with KCNJ14 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNJ14-to-partner and partner-to-KCNJ14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ14 versus MSH2 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ14→partner) and Y-score (partner→KCNJ14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH2 →	+0.472	+0.379	<.001	<.001	3	5
LSCC	SF3B3 →	+0.260	+0.569	<.001	<.001	3	5
LUAD	FOXK1 →	+0.369	+0.356	<.001	<.001	3	5
HNSC	XPO1 →	+0.238	+0.576	<.001	<.001	3	4
LSCC	XPO5 →	+0.416	+0.380	<.001	<.001	3	4
OV	MPRIP_S301 →	-0.694	-0.878	.005	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,049 associations by consensus.

KCNJ14 vs MSH2 — LSCC

Explore this scatter interactively →