Across TCGA patient cohorts, KCNJ11 protein abundance is significantly associated with the RNA expression of many other genes, with 495 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNJ11-associated genes across cancer lineages are DPP4, PLN, and DPP4-DT. Each is linked with KCNJ11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ11-to-partner and partner-to-KCNJ11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ11→partner) and Y-score (partner→KCNJ11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPP4 →	+1.568	+1.131	<.001	<.001	3	2
BRCA	PLN →	+2.213	+1.583	.001	.007	3	2
UCEC	DPP4-DT →	+1.105	+1.769	<.001	<.001	3	2
UCEC	PROCR →	+0.941	+1.400	.001	.001	3	1
UCEC	CST4 →	+1.813	+1.139	.004	.005	3	1
UCEC	VGLL1 →	-0.997	-1.332	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 495 associations by consensus.

Exploration

KCNJ11 survival (RNA) · tumor vs normal (RNA) · all KCNJ11 data types