KCNIP4-IT1

Across TCGA pan-cancer cohorts, KCNIP4-IT1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated KCNIP4-IT1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KCNIP4-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNIP4-IT1 expression acts as an unfavorable survival marker, although some lineages such as LAML and UVM show a favorable association.

KIRP, HNSC, and LIHC are the cancer types where KCNIP4-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.329	0.756	.003	51	view →
HNSC	DFS	Tertile	All	0.647	0.712	.009	48	view →
LIHC	OS	Tertile	All	0.529	0.792	.007	45	view →
THYM	DFS	Tertile	II,III,IV	0.180	0.753	<.001	42	view →
LAML	DFS	Median	All	0.636	0.250	<.001	36	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.675	<.001	36	view →
KIRC	DFS	Tertile	All	0.462	0.685	.008	32	view →
THCA	DFS	Tertile	III,IV	0.514	0.803	.013	18	view →
UVM	OS	Tertile	All	1.000	0.505	.027	12	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	12	view →
SKCM	DFS	Tertile	IV	0.041	0.519	<.001	9	view →
LGG	DFS	Median	All	0.346	0.514	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

KCNIP4-IT1–KIRP (OS)

Open the KIRP breakdown →