Across TCGA cell cohorts, KCNH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,998 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNH8-associated GO terms across cancer lineages are Positive regulation of syncytium formation by plasma membrane fusion, Regulation of mucus secretion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with KCNH8 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCNH8-to-partner and partner-to-KCNH8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH8→partner) and Y-score (partner→KCNH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of syncytium formation by plasma membrane fusion →	-0.138	-1.061	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of mucus secretion →	-0.837	-0.177	<.001	.001	3	7
BLOOD_Leukemia	Regulation of syncytium formation by plasma membrane fusion →	+0.066	+0.204	<.001	.002	3	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.074	+1.626	.002	.003	3	7
LUNG_SCLC	Low-density lipoprotein particle clearance →	-0.126	-1.837	.001	<.001	3	7
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.061	+1.648	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,998 associations by consensus.

Exploration

KCNH8 survival (RNA) · tumor vs normal (RNA) · all KCNH8 data types