KCNH4

Across TCGA cell cohorts, KCNH4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,187 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNH4-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Purine nucleoside triphosphate metabolic process, and ATP biosynthetic process. Each is linked with KCNH4 in more than 9 cancer types. Because this analysis shows association rather than direction, both KCNH4-to-partner and partner-to-KCNH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by KCNH4-low versus KCNH4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH4→partner) and Y-score (partner→KCNH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nucleoside triphosphate metabolic process →	+0.072	+0.930	<.001	<.001	3	10
STOMACH	Purine nucleoside triphosphate metabolic process →	+0.071	+0.639	<.001	.003	3	10
LUNG_SCLC	ATP biosynthetic process →	+0.093	+1.235	.003	<.001	2	10
STOMACH	ATP metabolic process →	+0.087	+0.676	<.001	.001	3	8
SKIN	Methylglyoxal catabolic process →	+0.123	+0.193	.002	.007	3	8
STOMACH	Cellular respiration →	+0.088	+0.587	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,187 associations by consensus.

Nucleoside triphosphate metabolic process by KCNH4 expression — LUNG_SCLC

Explore this box plot interactively →