KCNH3

Across TCGA patient cohorts, KCNH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,965 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNH3-associated proteins across cancer lineages are SDF2L1, SQOR, and TMF1. Each is linked with KCNH3 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNH3-to-partner and partner-to-KCNH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH3 versus SDF2L1 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH3→partner) and Y-score (partner→KCNH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SDF2L1 →	-0.412	-1.018	<.001	<.001	3	3
GBM	SQOR →	-0.627	-0.927	<.001	<.001	3	3
GBM	TMF1 →	-0.232	-0.764	<.001	<.001	3	3
OV	TRIP11 →	-0.339	-1.220	<.001	<.001	3	3
OV	UCHL1 →	+1.226	+0.950	<.001	.008	3	3
OV	CFAP36 →	+0.466	+1.315	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,965 associations by consensus.

KCNH3 vs SDF2L1 — GBM

Explore this scatter interactively →