KCNE2

Across TCGA patient cohorts, KCNE2 mutation is significantly associated with the RNA expression of many other genes, with 322 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNE2-associated genes across cancer lineages are LINC01607, H3C8, and RCC1L. Each is linked with KCNE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNE2-to-partner and partner-to-KCNE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01607 grouped by KCNE2-low versus KCNE2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNE2→partner) and Y-score (partner→KCNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01607 →	-0.734	-3.443	.001	.005	3	1
UCEC	H3C8 →	+0.728	+2.700	.003	.006	3	1
UCEC	RCC1L →	+0.328	+3.467	.009	.002	3	1
UCEC	UHRF1 →	+1.181	+3.470	<.001	.002	3	1
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
SKCM	ACTR6P1 →	+0.044	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 322 associations by consensus.

LINC01607 by KCNE2 expression — UCEC

Explore this box plot interactively →