KCND3

Across TCGA cell cohorts, KCND3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,981 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCND3-associated GO terms across cancer lineages are Negative regulation of stem cell differentiation, Regulation of organelle assembly, and Regulation of mRNA stability. Each is linked with KCND3 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCND3-to-partner and partner-to-KCND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell differentiation grouped by KCND3-low versus KCND3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCND3→partner) and Y-score (partner→KCND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of stem cell differentiation →	+0.214	+1.866	<.001	.002	3	5
SOFT_TISSUE	Regulation of organelle assembly →	+0.031	+1.008	<.001	<.001	3	5
SOFT_TISSUE	Regulation of mRNA stability →	+0.045	+0.672	<.001	.004	3	5
LARGE_INTESTINE	Hippocampus development →	+0.049	+0.154	.001	.008	2	6
SOFT_TISSUE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.165	+1.542	<.001	<.001	3	4
CNS	Pericardium morphogenesis →	+0.701	+0.538	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,981 associations by consensus.

Negative regulation of stem cell differentiation by KCND3 expression — LUNG_SCLC

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