KCNC4

Across TCGA patient cohorts, KCNC4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,444 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNC4-associated genes across cancer lineages are ANGPT4, PROKR2, and PPP1R16B. Each is linked with KCNC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNC4-to-partner and partner-to-KCNC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNC4 versus ANGPT4 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC4→partner) and Y-score (partner→KCNC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ANGPT4 →	+0.269	+0.597	.004	<.001	3	1
GBM	PROKR2 →	+0.237	+0.394	.003	.009	3	1
GBM	PPP1R16B →	+1.137	+0.432	.003	.003	3	1
GBM	PHEX →	-0.637	-0.536	<.001	.003	3	1
GBM	TUBB4A →	+1.873	+0.485	<.001	<.001	3	1
GBM	APLP1 →	+1.071	+0.441	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,444 associations by consensus.

KCNC4 vs ANGPT4 — GBM

Explore this scatter interactively →