KCNC3

Across TCGA patient cohorts, KCNC3 protein abundance is significantly associated with the RNA expression of many other genes, with 705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNC3-associated genes across cancer lineages are OTX1, SFTPA1, and RBM39. Each is linked with KCNC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNC3-to-partner and partner-to-KCNC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNC3 versus OTX1 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC3→partner) and Y-score (partner→KCNC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OTX1 →	+1.120	+0.535	.001	.002	3	1
GBM	SFTPA1 →	+0.601	+0.925	<.001	<.001	3	1
GBM	RBM39 →	+0.381	+0.533	.001	<.001	3	1
GBM	BTBD3 →	+0.658	+0.611	<.001	<.001	3	1
GBM	TNS3 →	-0.830	-0.455	<.001	.002	3	1
GBM	SURF1 →	-0.303	-0.680	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

KCNC3 vs OTX1 — GBM

Explore this scatter interactively →