KCNC1

Across TCGA cell cohorts, KCNC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNC1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Epigenetic regulation of gene expression, and Spliceosomal complex assembly. Each is linked with KCNC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both KCNC1-to-partner and partner-to-KCNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by KCNC1-low versus KCNC1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNC1→partner) and Y-score (partner→KCNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.070	+1.648	<.001	<.001	3	14
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.066	+1.566	.001	.001	3	13
LUNG_SCLC	Spliceosomal complex assembly →	+0.117	+1.783	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of DNA repair →	+0.072	+1.589	<.001	<.001	3	13
LUNG_SCLC	Regulation of DNA repair →	+0.072	+1.636	<.001	<.001	3	13
SOFT_TISSUE	Regulation of RNA splicing →	+0.077	+0.780	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

Positive regulation of DNA metabolic process by KCNC1 expression — LUNG_SCLC

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