KCNB2

Across TCGA cell cohorts, KCNB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,014 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KCNB2-associated GO terms across cancer lineages are Regulation of cytoplasmic translational elongation, Myeloid leukocyte mediated immunity, and Regulation of hemoglobin biosynthetic process. Each is linked with KCNB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNB2-to-partner and partner-to-KCNB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translational elongation grouped by KCNB2-low versus KCNB2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNB2→partner) and Y-score (partner→KCNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of cytoplasmic translational elongation →	-0.197	-1.996	<.001	<.001	3	4
LUNG_SCLC	Myeloid leukocyte mediated immunity →	+0.136	+2.680	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of hemoglobin biosynthetic process →	+0.121	+0.177	<.001	.004	3	3
UPPER_AERODIGESTIVE_TRACT	Positive regulation of hemoglobin biosynthetic process →	+0.135	+0.150	<.001	.006	3	3
URINARY_TRACT	Positive regulation of purine nucleotide biosynthetic process →	+0.115	+0.027	<.001	.003	2	4
URINARY_TRACT	Positive regulation of ATP biosynthetic process →	+0.115	+0.027	<.001	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,014 associations by consensus.

Regulation of cytoplasmic translational elongation by KCNB2 expression — LUNG_SCLC

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