KCNAB1

Across TCGA patient cohorts, KCNAB1 mutation is significantly associated with the RNA expression of many other genes, with 2,768 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNAB1-associated genes across cancer lineages are RNA5SP412, SNORD82, and TRAJ11. Each is linked with KCNAB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNAB1-to-partner and partner-to-KCNAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by KCNAB1-low versus KCNAB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNAB1→partner) and Y-score (partner→KCNAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.419	+1.493	<.001	.009	3	3
LUSC	SNORD82 →	+0.461	+2.862	<.001	.003	3	3
UCEC	TRAJ11 →	+0.390	+1.939	<.001	<.001	3	3
UCEC	MRPL49 →	+0.395	+1.890	.003	.001	3	2
UCEC	ALDOA →	+0.497	+2.222	<.001	<.001	3	2
UCEC	C18orf25 →	+0.407	+1.711	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,768 associations by consensus.

RNA5SP412 by KCNAB1 expression — UCEC

Explore this box plot interactively →