KCNAB1-AS2

Across TCGA pan-cancer cohorts, KCNAB1-AS2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KCNAB1-AS2 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher KCNAB1-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KCNAB1-AS2 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

KICH, COAD, and LUAD are the cancer types where KCNAB1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.399	0.913	<.001	93	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	75	view →
LUAD	DFS	Tertile	IV	0.163	0.738	.001	60	view →
KIRC	DFS	Median	III,IV	0.561	0.829	<.001	58	view →
READ	OS	Tertile	III,IV	0.330	0.900	<.001	54	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	45	view →
CESC	DFS	Tertile	II,III,IV	0.591	0.802	.010	36	view →
BLCA	OS	Tertile	III,IV	0.806	0.524	.017	21	view →
TGCT	DFS	Tertile	III,IV	0.017	0.923	.021	18	view →
HNSC	DFS	Tertile	All	0.631	0.725	.012	11	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	9	view →
MESO	OS	Tertile	IV	0.134	0.629	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

KCNAB1-AS2–KICH (DFS)

Open the KICH breakdown →