KCNA7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNA7 mutation is significantly associated with the RNA expression of many other genes, with 536 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNA7-associated genes across cancer lineages are MIR8082, RNU6-128P, and TRIM64EP. Each is linked with KCNA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNA7-to-partner and partner-to-KCNA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8082 grouped by KCNA7-low versus KCNA7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNA7→partner) and Y-score (partner→KCNA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR8082 →+0.329+2.424.001.00532
CESCRNU6-128P →+0.377+5.306<.001.00632
CESCTRIM64EP →+0.034+5.969<.001.00232
LUADRPL5P10 →+0.075+4.468.001.00232
LUADLINC01326 →+0.065+5.748.001.00132
SKCMRNU6-577P →+0.372+3.118<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 536 associations by consensus.

MIR8082 by KCNA7 expression — UCEC

Box plot of MIR8082 in KCNA7-low vs KCNA7-high samples in UCEC.

Explore this box plot interactively →

Exploration