KCNA10

Across TCGA pan-cancer cohorts, KCNA10 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KCNA10 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KCNA10 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated KCNA10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, OV, and LUSC are the cancer types where KCNA10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.300	.002	34	view →
OV	DFS	Median	II,III,IV	0.222	0.541	.038	18	view →
LUSC	DFS	Median	All	0.295	0.649	.011	6	view →
LIHC	OS	Median	All	0.215	0.674	.012	6	view →
SKCM	OS	Median	III,IV	0.944	0.779	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KCNA10–UCEC (DFS)

Open the UCEC breakdown →