KCMF1

Across TCGA cell cohorts, KCMF1 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCMF1-associated genes across cancer lineages are VN1R4, POM121L12, and PPP1R2C. Each is linked with KCMF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCMF1-to-partner and partner-to-KCMF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R4 grouped by KCMF1-low versus KCMF1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCMF1→partner) and Y-score (partner→KCMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	VN1R4 →	+0.098	+5.754	<.001	.002	3	1
LUNG_NSCLC_LUAD	POM121L12 →	+0.022	+5.266	<.001	.001	3	1
BLOOD_Leukemia	PPP1R2C →	+0.230	+4.539	<.001	.007	3	1
BLOOD_Leukemia	CST8 →	+0.046	+4.969	<.001	.003	3	1
BLOOD_Leukemia	OR5AN1 →	+0.080	+4.152	<.001	.009	3	1
LARGE_INTESTINE	TULP2 →	+0.143	+2.745	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

VN1R4 by KCMF1 expression — CNS

Explore this box plot interactively →