KBTBD8

Across TCGA patient cohorts, KBTBD8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KBTBD8-associated genes across cancer lineages are PDE1B, ABCD2, and TRAV41. Each is linked with KBTBD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD8-to-partner and partner-to-KBTBD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KBTBD8 versus PDE1B in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD8→partner) and Y-score (partner→KBTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDE1B →	+0.724	+0.723	.004	<.001	3	2
BRCA	ABCD2 →	+0.438	+0.700	<.001	<.001	3	2
BRCA	TRAV41 →	+0.790	+0.747	<.001	<.001	3	2
LSCC	GGCT →	-0.836	-0.469	.002	.002	3	2
LSCC	PAG1 →	+0.643	+0.367	.001	.007	3	2
HNSC	CDRT15P3 →	+0.201	+0.677	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,200 associations by consensus.

KBTBD8 vs PDE1B — BRCA

Explore this scatter interactively →