KBTBD8

Across TCGA cell cohorts, KBTBD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,169 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KBTBD8-associated GO terms across cancer lineages are Regulation of mitochondrial translation, Mitochondrial mRNA catabolic process, and Spermine biosynthetic process. Each is linked with KBTBD8 in more than 11 cancer types. Because this analysis shows association rather than direction, both KBTBD8-to-partner and partner-to-KBTBD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial translation grouped by KBTBD8-low versus KBTBD8-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD8→partner) and Y-score (partner→KBTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of mitochondrial translation →	+0.082	+0.719	.002	.003	3	12
BLOOD_Lymphoma	Mitochondrial mRNA catabolic process →	+0.090	+1.350	<.001	<.001	3	11
LIVER	Spermine biosynthetic process →	+0.146	+0.597	.002	<.001	3	11
KIDNEY	Regulation of mitochondrial mRNA stability →	+0.101	+0.501	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Microtubule polymerization or depolymerization →	+0.066	+0.365	<.001	.001	3	11
LIVER	Ribosomal large subunit assembly →	+0.148	+1.055	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,169 associations by consensus.

Regulation of mitochondrial translation by KBTBD8 expression — OVARY

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