KBTBD8

Across TCGA cell cohorts, KBTBD8 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KBTBD8-associated genes across cancer lineages are CRYGC, RBMY1F, and AGTR2. Each is linked with KBTBD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD8-to-partner and partner-to-KBTBD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGC grouped by KBTBD8-low versus KBTBD8-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD8→partner) and Y-score (partner→KBTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CRYGC →	+0.550	+4.169	<.001	.008	3	1
CNS	RBMY1F →	+0.195	+4.643	<.001	.003	3	1
CNS	AGTR2 →	+0.033	+4.643	<.001	.003	3	1
CNS	PRORY →	+1.078	+5.044	<.001	.001	3	1
CNS	RBMY1E →	+0.710	+4.169	.004	.008	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CRYGC by KBTBD8 expression — CNS

Explore this box plot interactively →