KBTBD4

Across TCGA patient cohorts, KBTBD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,709 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KBTBD4-associated proteins across cancer lineages are PCK2, ZKSCAN1, and THEMIS2. Each is linked with KBTBD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both KBTBD4-to-partner and partner-to-KBTBD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KBTBD4 versus PCK2 in GBM, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD4→partner) and Y-score (partner→KBTBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PCK2 →	-0.333	-0.211	.004	.008	3	5
LSCC	ZKSCAN1 →	+0.328	+0.290	<.001	<.001	3	4
GBM	THEMIS2 →	-0.540	-0.338	<.001	.001	3	4
GBM	NCF2 →	-0.777	-0.409	<.001	<.001	3	4
GBM	PLCG2 →	-0.653	-0.405	<.001	<.001	3	4
GBM	USP47 →	+0.212	+0.283	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,709 associations by consensus.

KBTBD4 vs PCK2 — GBM

Explore this scatter interactively →