KBTBD4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KBTBD4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,102 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KBTBD4-associated genes across cancer lineages are ERBB4, TRIM44, and AGBL2. Each is linked with KBTBD4 in more than 2 cancer types. Because this analysis shows association rather than direction, both KBTBD4-to-partner and partner-to-KBTBD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KBTBD4 versus ERBB4 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD4→partner) and Y-score (partner→KBTBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAERBB4 →+1.589+0.304<.001<.00133
HNSCTRIM44 →+0.649+0.316<.001<.00133
OVAGBL2 →+0.747+0.403.006.00133
BRCALINC00339 →+0.521+0.253<.001<.00133
HNSCCELF1 →+0.565+0.323<.001<.00133
BRCADDB2 →+0.394+0.188<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,102 associations by consensus.

KBTBD4 vs ERBB4 — BRCA

Per-sample scatter of KBTBD4 vs ERBB4 in BRCA (Pearson r = 0.39).

Explore this scatter interactively →

Exploration