KBTBD3

Across TCGA patient cohorts, KBTBD3 mutation is significantly associated with the RNA expression of many other genes, with 1,254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KBTBD3-associated genes across cancer lineages are PNMA6E, LINC00709, and RNU2-13P. Each is linked with KBTBD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD3-to-partner and partner-to-KBTBD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNMA6E grouped by KBTBD3-low versus KBTBD3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD3→partner) and Y-score (partner→KBTBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PNMA6E →	+0.096	+3.843	<.001	.004	3	2
COAD	LINC00709 →	+0.088	+5.142	.002	.002	3	2
COAD	RNU2-13P →	+0.223	+4.917	<.001	.003	3	2
SKCM	RPL29P32 →	+0.026	+4.485	<.001	.004	3	2
UCEC	AP1S3 →	+0.384	+1.789	.009	.008	3	2
BRCA	TSPY22P →	+0.049	+8.471	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,254 associations by consensus.

PNMA6E by KBTBD3 expression — COAD

Explore this box plot interactively →