KBTBD2

Across TCGA cell cohorts, KBTBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,657 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KBTBD2-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Golgi vesicle transport, and Heterochromatin formation. Each is linked with KBTBD2 in more than 14 cancer types. Because this analysis shows association rather than direction, both KBTBD2-to-partner and partner-to-KBTBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by KBTBD2-low versus KBTBD2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD2→partner) and Y-score (partner→KBTBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.076	+0.786	<.001	<.001	3	15
STOMACH	Golgi vesicle transport →	+0.062	+0.626	.002	<.001	3	14
STOMACH	Heterochromatin formation →	+0.067	+0.391	<.001	.004	3	14
SOFT_TISSUE	Regulation of chromosome segregation →	+0.133	+0.753	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.078	+0.722	<.001	<.001	3	14
BREAST	Positive regulation of chromosome organization →	+0.084	+0.709	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,657 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by KBTBD2 expression — BREAST

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