KBTBD2

Across TCGA cell cohorts, KBTBD2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KBTBD2-associated genes across cancer lineages are REG1B, OR10R2, and HTR3D. Each is linked with KBTBD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD2-to-partner and partner-to-KBTBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by KBTBD2-low versus KBTBD2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD2→partner) and Y-score (partner→KBTBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	2
BLOOD_Leukemia	OR10R2 →	+1.412	+3.551	<.001	.009	3	2
BLOOD_Lymphoma	HTR3D →	+0.020	+6.247	<.001	<.001	3	1
BLOOD_Leukemia	GHRHR →	+0.370	+3.705	<.001	.007	3	1
BLOOD_Leukemia	TCF21 →	+0.015	+3.705	<.001	.007	3	1
BLOOD_Leukemia	BTBD16 →	+0.092	+3.959	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

REG1B by KBTBD2 expression — BREAST

Explore this box plot interactively →