KBTBD13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KBTBD13 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KBTBD13-associated genes across cancer lineages are ADIPOQ, MSGN1, and TAFA1. Each is linked with KBTBD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KBTBD13-to-partner and partner-to-KBTBD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADIPOQ grouped by KBTBD13-low versus KBTBD13-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KBTBD13→partner) and Y-score (partner→KBTBD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaADIPOQ →+0.006+5.209.006.00531
LARGE_INTESTINEMSGN1 →+0.126+4.930<.001.00131
LARGE_INTESTINETAFA1 →+0.410+4.273<.001.00631
LARGE_INTESTINELCE1F →+0.122+4.415<.001.00731
SKINCFC1B →+0.070+6.022<.001.00131
SKINSPATA31D4 →+0.205+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ADIPOQ by KBTBD13 expression — BLOOD_Lymphoma

Box plot of ADIPOQ in KBTBD13-low vs KBTBD13-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration